INFAI

 

NMR Spectroscopy and NMR Imaging Services available from INFAI

INFAI offers a full range of NMR Spectroscopy and NMR Imaging services together with R&D projects, training and consultancy services.

Applications

The services offered in the fields of NMR spectroscopy and NMR microscopy range from R&D to industrial applications.

NMR-Spectroscopy

  • Identification of unknown substances
  • Determination of chemical structure of new synthetic compounds and/or natural products
  • Determination of substitution level of a derivatized material
  • Chemical kinetics
  • Qualitative and quantitative evaluation of compounds present in a mixture
  • Analysis of body fluids for diagnosis of metabolic diseases
  • Clinical studies for evaluating new drugs
  • Environmental analysis
  • Determination of the origin of high-quality foodstuffs such as wine and honey
  • Morphologic investigations of human tumours such as melanoma
  • Quality control for industrial products
  • Optimisation of production processes in order to save costs and material
  • Research and development of new products and processes
  • Consulting services for development, implementation and evaluation of analytical procedures

High-Throughput NMR-Spectroscopy

  • Database screening
  • Structural measurements in combinatorical chemistry
  • Screening of body fluids
  • Metabolite screening for the optimisation of drug dosages

NMR-Imaging

  • Morphological analyses and identification of biologic tissue, e.g. skin tumours, for early recognition of malign melanomas
  • Non-invasive display of the internal structure of small animals not exceeding the size of an average mouse.
  • 3D images of body organs
  • Imaging of the dissolution process of solid drugs for oral administration
  • Morphological analysis of plants
  • Determination of the molecular structure and microstructure of polymers
  • Determination of the impact of humidity and temperature on characteristic mechanical values and the chemical structure of polymers

NMR Spectroscopy and NMR Imaging are ideal methods for analysing a wide range of biological, chemical and medical samples. For these analyses INFAI laboratories are equipped with the following state-of-the-art technologies:

Samples and material

  • Organic and some inorganic materials [Spectroscopy]
  • Pharmaceuticals [Spectroscopy]
  • Biological and medical samples [Spectroscopy]
  • Body fluids such as plasma, urine, liquor [Spectroscopy]
  • Natural products including peptides, carbohydrates, lipids, vitamins, terpenes [Spectroscopy]
  • Mineral oil and mineral oil products [Spectroscopy]
  • Paint and varnish, excipients [Spectroscopy]
  • Toxic waste materials and pollutants [Spectroscopy]
  • Surgical biopsy samples [Spectroscopy, Microscopy]
  • Food products [Spectroscopy, Microscopy]
  • Monomers, polymers, resins [Spectroscopy, Microscopy]
  • Surface quality [Microscopy]

Technical equipment

  • Bruker ARX500 NMR-Spectrometer magnetic field strength 11,7 T
  • Bruker AM400 WB NMR-Spectrometer magnetic field strength 9,4  T
  • IMAGE-Equipment for creation of NMR images
  • Probeheads of 1H, 2H, 13C and X nuclei
  • Diverse probeheads for recording of NMR images
  • z-gradient unit
  • Workstations for evaluation of spectra and images, as well as for realisation of mathematic processes and interpretation of measuring results
  • Data backup on CD-ROM or Tape

More detailed information on specific applications of NMR spectroscopy and NMR imaging are presented on our web pages 'Spectroscopy' and 'Microscopy'. For additional information contact us at :

INFAI GmbH
Gottfried-Hagen-Str. 60-62
D-51105 Köln, Germany 
Fon: ++49 221 880 44 3
Fax: ++49 221 880 44 55 
e-mail: mail@infai.de


Please email us for more information

Copyright © 1997 INFAI GmbH
This Page was created by Peter Bast, 01/16/98
Most recent revision